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Article

Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer

31 Mar 2021

Abstract excerpt

Objective: The aim of the present study was repositioning of ivermectin in treatment of gastric cancer (GC) by computational prediction based on gene expression profiles of human and mouse model of GC and validations with in silico, in vitro and in vivo approaches. Methods: Computational drug repositioning was performed using connectivity map (cMap) and data/pathway mining with the Ingenuity Knowledge Base....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33867984
DOI: 10.3389/fphar.2021.625991

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