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Article

Trilobatin Induces Apoptosis and Attenuates Stemness Phenotype of Acquired Gefitinib Resistant Lung Cancer Cells via Suppression of NF-κB Pathway.

Nutrition and cancer - 1 Jan 2022

Li Wang, Zihan Xu, Yizhe Wei, Yanyang Liu, Zhixi Li, Xi Yan

Abstract excerpt

Trilobatin is a common type of flavonoids compounds derived from Lithocarpus polystachyus Rehd leaves. Previous report suggests that trilobatin was potentially involved in pro-and anticancer, antioxidative and anti-hyperglycemic activities. Here, we investigated the anticancer efficiency of trilobatin on gefitinib resistant lung cancer cells. In this study, MTT assays, EdU incorporation assays, DAPI staining,...

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Identifiers

PMID: 33860693
DOI: 10.1080/01635581.2021.1912368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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