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Article

Effect of 5-azacytidine (5-aza) on UCP2 expression in human liver and colon cancer cells

1 Jan 2021

Abstract excerpt

The function of the uncoupling protein 2 (UCP2) is different for each cancer cell. However, the mechanism of expression is still unclear. DNA methylation affects protein expression and is one factor that transforms normal cells into cancer cells. In this study, the hepatocellular carcinoma Hep3B and HepG2 cells and colorectal cancer HT-29 cells were treated with 5-azacytidine (5-aza), a DNA demethylation agent,...

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PMID: 33859525
DOI: 10.7150/ijms.56564

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