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Overexpressing PTTG family genes predict poor prognosis in kidney renal clear cell carcinoma

12 Apr 2021

Abstract excerpt

BACKGROUND: Pituitary tumor transforming genes (PTTG1, PTTG2, and PTTG3P) play key roles in the pathogenesis and development of human cancers. The studies show that overexpression of the PTTG genes is associated with tumor progression and migration. However, the function of the PTTG genes in the prognostic value of kidney renal clear cell carcinoma is rarely known by people. METHODS: The expression of PTTG family...

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PMID: 33845847
DOI: 10.1186/s12957-021-02225-2

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