Article
Trametinib and dabrafenib induced rhabdomyolysis, renal failure, and visual loss. Report of one case.
Revista medica de Chile - 1 Nov 2020
Finsterer Josef
Abstract excerpt
MEK- and BRAF-inhibitors trametinib and dabrafenib are successfully used for BRAF-mutated, metastasizing melanoma, but these compounds may induce side effects. We report a 50 years old female with BRAF-mutated metastasizing melanoma who received trametinib (2 mg/d) and dabrafenib (200 mg/d) after using interferon without benefit. Shortly after starting trametinib/dabrafenib, she experienced an inability to abduct...
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