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What Every Neuropathologist Needs to Know: Practical Aspects and Pitfalls in Molecular Diagnosis of Brain Tumors.

Journal of neuropathology and experimental neurology - 16 Apr 2021

Stephen Nix J, Ida Cristiane M

Abstract excerpt

Molecular testing has become part of the routine diagnostic workup of brain tumors after the implementation of integrated histomolecular diagnoses in the 2016 WHO classification update. It is important for every neuropathologist to be aware of practical preanalytical, analytical, and postanalytical factors that impact the performance and interpretation of molecular tests. Prior to testing, optimizing tumor purity...

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PMID: 33837419
DOI: 10.1093/jnen/nlab033

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