Article
LncRNA NEAT1 contributes to the acquisition of a tumor like-phenotype induced by PM 2.5 in lung bronchial epithelial cells via HIF-1α activation.
Environmental science and pollution research international - 1 Aug 2021
Jiang Pan, Hao Shengyu, Xie Liang, Xiang Guiling, Hu Weiping, Wu Qinhan, Liu Zilong, Li Shanqun
Abstract excerpt
The hazards of particulate matter (PM2.5) on human respiratory health have been previously reported. However, the molecular mechanisms underlying PM2.5-induced lung carcinogenesis have rarely been studied. In the present study, we explored the effects of PM2.5 on the epithelial-mesenchymal transition (EMT) and acquisition of cancer stem cell (CSC)-like properties in lung bronchial epithelial cells. We found that...
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