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Article

Prevalence and clinical phenotype of the triplicated α-globin genes and its ethnic and geographical distribution in Guizhou of China.

BMC medical genomics - 7 Apr 2021

Luo Xi, Zhang Xiang-Mei, Wu Liu-Song, Chen Jindong, Chen Yan

Abstract excerpt

BACKGROUND: α-thalassemia is relatively endemic in Guizhou province of southwestern China. To predict the clinical manifestations of α-globin gene aberration for genetic counseling, we examined the prevalence of the α-globin triplication and the genotype-phenotype correlation in this subpopulation METHODS: A cohort of 7644 subjects was selected from nine ethnicities covering four regions in Guizhou province of...

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Identifiers

PMID: 33827577
DOI: 10.1186/s12920-021-00944-9
PMCID: PMC8025570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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