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Article

Podocalyxin is a key negative regulator of human endometrial epithelial receptivity for embryo implantation

29 Jan 2021

Abstract excerpt

STUDY QUESTION: How is endometrial epithelial receptivity, particularly adhesiveness, regulated at the luminal epithelial surface for embryo implantation in the human? SUMMARY ANSWER: Podocalyxin (PCX), a transmembrane protein, was identified as a key negative regulator of endometrial epithelial receptivity; specific downregulation of PCX in the luminal epithelium in the mid-secretory phase, likely mediated by...

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PMID: 33822049
DOI: 10.1093/humrep/deab032

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