Article
Whole-exome sequencing analysis in 10 families of sporadic microtia with thoracic deformities.
Molecular genetics & genomic medicine - 1 May 2021
Yang Meirong, Lu Xiaosheng, Zhang Ye, Wang Changchen, Cai Zhen, Li Zhengyong, Pan Bo, Jiang Haiyue
Abstract excerpt
BACKGROUND: Microtia is a congenital malformation of the external ear and may occur as an isolated deformity or as part of a syndrome. Our previous study found a high correlation between microtia and thoracic deformities, thus, we propose that external ear and thorax development may be regulated by certain genes in common. METHODS: We performed exome sequencing on 10 families of sporadic microtia with thoracic...
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