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MALDI-TOF MS Biomarker Detection Models to Distinguish RTX Toxin Phenotypes of Moraxella bovoculi Strains Are Enhanced Using Calcium Chloride Supplemented Agar.

Frontiers in cellular and infection microbiology - 1 Jan 2021

Hille Matthew M, Clawson Michael L, Dickey Aaron M, Lowery Justin H, Loy John Dustin

Abstract excerpt

Moraxella bovoculi is the bacterium most often cultured from ocular lesions of cattle with infectious bovine keratoconjunctivitis, also known as bovine pinkeye. Some strains of M. bovoculi contain operons encoding for a repeats-in-toxin (RTX) toxin, which is a known virulence factor of multiple veterinary pathogens. We explored the utility of MALDI-TOF MS and biomarker detection models to classify the presence or...

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PMID: 33796479
DOI: 10.3389/fcimb.2021.632647
PMCID: PMC8007961

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