Article
Assessing the Function of the ZFP90 Variant rs1170426 in SLE and the Association Between SLE Drug Target and Susceptibility Genes.
Frontiers in immunology - 1 Jan 2021
Zhu Tingting, Huang Yuandi, Qian Danfeng, Sheng Yuming, Zhang Chaowen, Chen Shirui, Zhang Hui, Wang Hui, Zhang Xuejun, Liu Junlin, Ding Changhai, Liu Lu
Abstract excerpt
A genome-wide association study (GWAS) has discovered that a polymorphism in the ZFP90 gene is associated with systemic lupus erythematosus (SLE). In this study, we explored the candidate function of a ZFP90 variant (rs1170426) in the context of SLE and detected the relationship between SLE susceptible genes and SLE drug target genes. First, we investigated the regulatory role of rs1170426 on ZFP90 expression by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.