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A signature based on 11 autophagy genes for prognosis prediction of colorectal cancer

26 Oct 2021

Abstract excerpt

AIM: To develop an autophagy-gene-based signature that could help to anticipate the therapeutic effects of Colorectal Cancer (CRC). METHODS: We downloaded the gene expression profiles of CRC samples from the Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) datasets. Genes with significant prognostic value in CRC were screened through univariate Cox regression analysis, while the LASSO Cox...

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Autophagy in Disease and Therapy
Cancer Immunotherapy and Biomarkers
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34699544
DOI: 10.1371/journal.pone.0258741

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