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Article

A Novel and Reliable Rat Model of Autism

12 Mar 2021

Abstract excerpt

Background: Autism spectrum disorders (ASD) is a complex neurodevelopmental disorder that lacks an ideal animal model to recapitulate the disease state of ASD. Previous studies have reported that transplanting gut microbiota of ASD patients into pregnant mice is sufficient to promote the changes of autism-like behavior in offspring. This study aims to explore whether fecal microbiota transplantation (FMT) can be...

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PMID: 33776811
DOI: 10.3389/fpsyt.2021.549810

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