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Article

Prebiotic diet normalizes aberrant immune and behavioral phenotypes in a mouse model of autism spectrum disorder.

Acta pharmacologica Sinica - 1 Aug 2024

Prince Naika, Peralta Marzal Lucia N, Markidi Anastasia, Ahmed Sabbir, Adolfs Youri, Pasterkamp R Jeroen, Kumar Himanshu, Roeselers Guus, Garssen Johan, Kraneveld Aletta D, Perez-Pardo Paula

Abstract excerpt

Autism spectrum disorder (ASD) is a cluster of neurodevelopmental disorders characterized by deficits in communication and behavior. Increasing evidence suggests that the microbiota-gut-brain axis and the likely related immune imbalance may play a role in the development of this disorder. Gastrointestinal deficits and gut microbiota dysfunction have been linked to the development or severity of autistic behavior....

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Identifiers

PMID: 38589690
DOI: 10.1038/s41401-024-01268-x
PMCID: PMC11272935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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