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Differentially-expressed mRNAs, microRNAs and long noncoding RNAs in intervertebral disc degeneration identified by RNA-sequencing

1 Jan 2021

Abstract excerpt

The underlying molecular mechanisms of intervertebral disc degeneration (IDD) remain unclear. This study aimed to identify the crucial molecules and explore the function of noncoding RNAs and related pathways in IDD. We randomly selected three samples each from an IDD and a spinal cord injury group (control) for RNA-sequencing. We identified 463 differentially-expressed long noncoding RNAs (lncRNAs), 47...

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Cancer-related molecular mechanisms research
Osteoarthritis Treatment and Mechanisms
Spine and Intervertebral Disc Pathology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33764282
DOI: 10.1080/21655979.2021.1899533

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