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Article

Comparative in silico genome analysis of Clostridium perfringens unravels stable phylogroups with different genome characteristics and pathogenic potential.

Scientific reports - 24 Mar 2021

Abdel-Glil Mostafa Y, Thomas Prasad, Linde Jörg, Busch Anne, Wieler Lothar H, Neubauer Heinrich, Seyboldt Christian

Abstract excerpt

Clostridium perfringens causes a plethora of devastating infections, with toxin production being the underlying mechanism of pathogenicity in various hosts. Genomic analyses of 206 public-available C. perfringens strains´ sequence data identified a substantial degree of genomic variability in respect to episome content, chromosome size and mobile elements. However, the position and order of the local collinear...

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Identifiers

PMID: 33762628
DOI: 10.1038/s41598-021-86148-8
PMCID: PMC7991664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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