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Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients

1 Mar 2021

Abstract excerpt

To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a systematic way. We generate a linear epitope landscape of the Spike protein by analyzing the serum immunoglobulin G (IgG) response of 1,051 coronavirus disease 2019 (COVID-19) patients with a peptide microarray. We reveal two...

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PMID: 33761319
DOI: 10.1016/j.celrep.2021.108915

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