Article
Triple negative aggressive phenotype controlled by miR-135b and miR-365: new theranostics candidates.
Scientific reports - 22 Mar 2021
Bertoli Gloria, Cava Claudia, Corsi Fabio, Piccotti Francesca, Martelli Cristina, Ottobrini Luisa, Vaira Valentina, Castiglioni Isabella
Abstract excerpt
Triple negative breast cancer (TNBC) accounts for about a fifth of all breast cancers and includes a diverse group of cancers. The heterogeneity of TNBC and the lack of target receptors on the cell surface make it difficult to develop specific therapeutic treatments. These aspects cause the high negative prognosis of patients with this type of tumor. The analysis of the molecular profiles of TNBC samples has...
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