Article
Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus.
Diabetes & metabolism journal - 1 Jul 2021
Rattanatham Rujikorn, Settasatian Nongnuch, Komanasin Nantarat, Kukongviriyapan Upa, Sawanyawisuth Kittisak, Intharaphet Phongsak, Senthong Vichai, Settasatian Chatri
Abstract excerpt
BACKGROUND: Vascular complications are the major morbid consequences of type 2 diabetes mellitus (T2DM). The transcription factor 7-like 2 (TCF7L2), potassium voltage-gated channel subfamily Q member 1 (KCNQ1), and inwardly-rectifying potassium channel, subfamily J, member 11 gene (KCNJ11) are common T2DM susceptibility genes in various populations. However, the associations between polymorphisms in these genes...
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