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Article

High SLC2A1 expression associated with suppressing CD8 T cells and B cells promoted cancer survival in gastric cancer.

PloS one - 1 Jan 2021

Min Kyueng-Whan, Kim Dong-Hoon, Son Byoung Kwan, Moon Kyoung Min, Kim So Myoung, Intazur Rahaman Md, Kim So Won, Kim Eun-Kyung, Kwon Mi Jung, Koh Young Wha, Oh Il Hwan

Abstract excerpt

High expression of glucose transporter family members, which augment glucose uptake and glycolytic flux, has been shown to play a pivotal role in the proliferation and survival of tumor cells, contributing to the energy supply, biosynthesis and homeostasis of cancer cells. Among the many members, solute carrier family 2 member 1 (SLC2A1) encodes a glucose transporter, GLUT1, that is critical in the metabolism of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33735188
DOI: 10.1371/journal.pone.0245075
PMCID: PMC7971512

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