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Article

Reactive Oxygen Species in Autoimmune Cells: Function, Differentiation, and Metabolism.

Frontiers in immunology - 1 Jan 2021

Lin Weiji, Shen Pan, Song Yaqin, Huang Ying, Tu Shenghao

Abstract excerpt

Accumulated reactive oxygen species (ROS) directly contribute to biomacromolecule damage and influence various inflammatory responses. Reactive oxygen species act as mediator between innate and adaptive immune cells, thereby influencing the antigen-presenting process that results in T cell activation. Evidence from patients with chronic granulomatous disease and mouse models support the function of ROS in...

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Identifiers

PMID: 33717180
DOI: 10.3389/fimmu.2021.635021
PMCID: PMC7946999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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