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Article

Bioinformatics-based prediction of conformational epitopes for Enterovirus A71 and Coxsackievirus A16.

Scientific reports - 11 Mar 2021

Wang Liping, Zhu Miao, Fang Yulu, Rong Hao, Gao Liuying, Liao Qi, Zhang Lina, Dong Changzheng

Abstract excerpt

Enterovirus A71 (EV-A71), Coxsackievirus A16 (CV-A16) and CV-A10 are the major causative agents of hand, foot and mouth disease (HFMD). The conformational epitopes play a vital role in monitoring the antigenic evolution, predicting dominant strains and preparing vaccines. In this study, we employed a Bioinformatics-based algorithm to predict the conformational epitopes of EV-A71 and CV-A16 and compared with that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33707530
DOI: 10.1038/s41598-021-84891-6
PMCID: PMC7952546

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