Article
The crest phenotype in domestic chicken is caused by a 197 bp duplication in the intron of HOXC10.
G3 (Bethesda, Md.) - 9 Feb 2021
Li Jingyi, Lee Mi-Ok, Davis Brian W, Wu Ping, Hsieh Li Shu-Man, Chuong Cheng-Ming, Andersson Leif
Abstract excerpt
The Crest mutation in chicken shows incomplete dominance and causes a spectacular phenotype in which the small feathers normally present on the head are replaced by much larger feathers normally present only in dorsal skin. Using whole-genome sequencing, we show that the crest phenotype is caused by a 197 bp duplication of an evolutionarily conserved sequence located in the intron of HOXC10 on chromosome 33. A...
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