Article
Exosomes for mRNA delivery: a novel biotherapeutic strategy with hurdles and hope
10 Mar 2021
Abstract excerpt
Over the past decade, therapeutic messenger RNAs (mRNAs) have emerged as a highly promising new class of drugs for protein replacement therapies. Due to the recent developments, the incorporation of modified nucleotides in synthetic mRNAs can lead to maximizing protein expression and reducing adverse immunogenicity. Despite these stunning improvements, mRNA therapy is limited by the need for the development of...
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