Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition

Abstract excerpt

At implantation, the embryo establishes contacts with the maternal endometrium. This stage is associated with a high incidence of preclinical pregnancy losses. While the maternal factors underlying uterine receptivity have been investigated, the signals required by the embryo for successful peri-implantation development remain elusive. To explore these, we studied integrin β1 signaling, as embryos deficient for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Organ and Tissue Transplantation Research
• Share to Reproductive Biology and Fertility
• Share to Reproductive System and Pregnancy