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Gene therapy for inherited retinal diseases: progress and possibilities

2 Mar 2021

Abstract excerpt

Inherited retinal diseases (IRDs) comprise a heterogeneous group of genetic disorders affecting the retina. Caused by mutations in over 300 genes, IRDs result in visual impairment due to dysfunction and degeneration of photoreceptors, retinal pigment epithelium, or the choroid. Important photoreceptor IRDs include retinitis pigmentosa and Leber congenital amaurosis. Macular dystrophies include Stargardt and Best...

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PMID: 33689657
DOI: 10.1080/08164622.2021.1880863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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