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Alterations of Extracellular Matrix Components in the Course of Juvenile Idiopathic Arthritis

25 Feb 2021

Abstract excerpt

Juvenile idiopathic arthritis (JIA) is the most common group of chronic connective tissue diseases in children that is accompanied by joint structure and function disorders. Inflammation underlying the pathogenic changes in JIA, caused by hypersecretion of proinflammatory cytokines, leads to the destruction of articular cartilage. The degradation which progresses with the duration of JIA is not compensated by the...

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PMID: 33668781
DOI: 10.3390/metabo11030132

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