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Article

Host Genome-Wide Association Study of Infant Susceptibility to Shigella-Associated Diarrhea.

Infection and immunity - 17 May 2021

Duchen Dylan, Haque Rashidul, Chen Laura, Wojcik Genevieve, Korpe Poonum, Nayak Uma, Mentzer Alexander J, Kirkpatrick Beth, Petri William A, Duggal Priya

Abstract excerpt

Shigella is a leading cause of moderate-to-severe diarrhea globally and the causative agent of shigellosis and bacillary dysentery. Associated with 80 to 165 million cases of diarrhea and >13% of diarrheal deaths, in many regions, Shigella exposure is ubiquitous while infection is heterogenous. To characterize host-genetic susceptibility to Shigella-associated diarrhea, we performed two independent genome-wide...

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Identifiers

PMID: 33649051
DOI: 10.1128/IAI.00012-21
PMCID: PMC8316060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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