Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of Monogenic Candidate Genes for Human Nephrotic Syndrome Using 3 Independent Approaches

3 Dec 2020

Abstract excerpt

Introduction Steroid-resistant nephrotic syndrome (SRNS) is the second most common cause of chronic kidney disease during childhood. Identification of 63 monogenic human genes has delineated 12 distinct pathogenic pathways. Methods Here, we generated 2 independent sets of nephrotic syndrome (NS) candidate genes to augment the discovery of additional monogenic causes based on whole-exome sequencing (WES) data from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloidosis: Diagnosis, Treatment, Outcomes
Share to Renal and related cancers
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33615071
DOI: 10.1016/j.ekir.2020.11.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of Monogenic Candidate Genes for Human Nephrotic Syndrome Using 3 Independent ApproachesPMID 33615071Read ↗

Monogenic Causes Identified in 23.68% of Children with Steroid-Resistant Nephrotic Syndrome: A Single-Centre StudySemantic proximity Read ↗

Whole genome sequencing identifies monogenic disease in 56.1% of families with early-onset steroid-resistant nephrotic syndromeSemantic proximity Read ↗

Genetic kidney diseases.Semantic proximity Read ↗

A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome.Semantic proximity Read ↗

Analysis of 24 genes reveals a monogenic cause in 11.1% of cases with steroid-resistant nephrotic syndrome at a single center.Semantic proximity Read ↗

Translating genetic findings in hereditary nephrotic syndrome: the missing loopsSemantic proximity Read ↗

Identification of monogenic variants in steroid-resistant and steroid-sensitive nephrotic syndrome.Semantic proximity Read ↗

Diagnosis of monogenic chronic kidney diseasesSemantic proximity Read ↗

Whole exome sequencing identifies monogenic forms of nephritis in a previously unsolved cohort of children with steroid-resistant nephrotic syndrome and hematuria.Semantic proximity Read ↗

Evaluating Mendelian nephrotic syndrome genes for evidence of risk alleles or oligogenicity that explain heritabilitySemantic proximity Read ↗

Advances in molecular diagnosis and therapeutics in nephrotic syndrome and focal and segmental glomerulosclerosis.Semantic proximity Read ↗

Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic Syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.