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Article

Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype.

mSphere - 17 Feb 2021

Jones Jane T, Liu Ko-Wei, Wang Xi, Kowalski Caitlin H, Ross Brandon S, Mills Kathleen A M, Kerkaert Joshua D, Hohl Tobias M, Lofgren Lotus A, Stajich Jason E, Obar Joshua J, Cramer Robert A

Abstract excerpt

Aspergillus fumigatus is a filamentous fungus which can cause multiple diseases in humans. Allergic broncho-pulmonary aspergillosis (ABPA) is a disease diagnosed primarily in cystic fibrosis patients caused by a severe allergic response often to long-term A. fumigatus colonization in the lungs. Mice develop an allergic response to repeated inhalation of A. fumigatus spores; however, no strains have been...

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Identifiers

PMID: 33597172
DOI: 10.1128/mSphere.01250-20
PMCID: PMC8544898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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