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The ecdysone-induced protein 93 is a key factor regulating gonadotrophic cycles in the adult female mosquito Aedes aegypti

15 Feb 2021

Abstract excerpt

Significance In female mosquitoes, repeated blood feedings are essential for maintaining gonadotrophic cycles and serve as the basis for pathogen transmission. We demonstrate that the ecdysone-induced protein 93 (E93), a transcription factor implicated in insect metamorphic transitions, regulates reproductive switches in adult females of the major arboviral vector Aedes aegypti . E93 RNA interference before the...

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PMID: 33593917
DOI: 10.1073/pnas.2021910118

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