Prevalence and Distribution of Major β-Thalassemia Mutations and HbE/β-Thalassemia Variant in Nepalese Ethnic Groups.

doi:10.1016/j.hemonc.2021.01.004

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Article

Prevalence and Distribution of Major β-Thalassemia Mutations and HbE/β-Thalassemia Variant in Nepalese Ethnic Groups.

Hematology/oncology and stem cell therapy - 1 Mar 2022

Lama Raju, Yusof Wardah, Shrestha Tilak R, Hanafi Sarifah, Bhattarai Matrika, Hassan Rosline, Zilfalil Bin Alwi

Abstract excerpt

BACKGROUND: Beta-thalassemia is a genetic disorder that is inherited in an autosomal recessive pattern. This genetic disease leads to a defective beta-globin hemoglobin chain causing partial or complete beta-globin chain synthesis loss. Beta-thalassemia major patients need a continuous blood tran...

Topics

Humans
beta-Thalassemia
Nepal
DNA Mutational Analysis
Ethnicity
Prevalence
Cadmium
beta-Globins
Mutation
Thalassemia

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