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Deep learning detects genetic alterations in cancer histology generated by adversarial networks

9 Feb 2021

Abstract excerpt

Deep learning can detect microsatellite instability (MSI) from routine histology images in colorectal cancer (CRC). However, ethical and legal barriers impede sharing of images and genetic data, hampering development of new algorithms for detection of MSI and other biomarkers. We hypothesized that histology images synthesized by conditional generative adversarial networks (CGANs) retain information about genetic...

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PMID: 33565124
DOI: 10.1002/path.5638

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