Article
Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster.
Molecular biology and evolution - 4 May 2021
Johnstun Joel A, Shankar Vijay, Mokashi Sneha S, Sunkara Lakshmi T, Ihearahu Ugonna E, Lyman Roberta L, Mackay Trudy F C, Anholt Robert R H
Abstract excerpt
Large multigene families, such as the insect odorant-binding proteins (OBPs), are thought to arise through functional diversification after repeated gene duplications. Whereas many OBPs function in chemoreception, members of this family are also expressed in tissues outside chemosensory organs. Paralogs of the Obp50 gene cluster are expressed in metabolic and male reproductive tissues, but their functions and...
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