Article
Identifying obstetrics patients in whom RHD genotyping can be used to assess risk of D alloimmunization.
Immunohematology - 1 Dec 2020
Horn Trina N, Keller Jessica, Keller Margaret A, Klinger Liz
Abstract excerpt
CONCLUSIONS: The D antigen is highly immunogenic and may cause alloimmunization to occur after blood transfusion or pregnancy. Some RHD variant alleles express a D antigen that is missing one or more epitopes, thus putting a presumed D+ patient at risk for alloanti-D and hemolytic disease of the fetus and newborn. It is generally accepted that individuals who have a serologic weak D phenotype due to one of three...
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