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Article

INF2 p.Arg214Cys mutation in a Chinese family with rapidly progressive renal failure and follow-up of renal transplantation: case report and literature review.

BMC nephrology - 4 Feb 2021

Zhao Wenbo, Ma Xinxin, Zhang Xiaohao, Luo Dan, Zhang Jun, Li Ming, Ye Zengchun, Peng Hui

Abstract excerpt

BACKGROUND: Heterozygous mutations in the inverted formin 2 (INF2) gene are related to secondary focal segmental glomerulosclerosis (FSGS), a rare secondary disease associated with rapidly progressive renal failure. CASE PRESENTATION: We report a patient with familial autosomal INF2 mutation manifesting nephritic syndromes and elevated serum creatinine levels. Mutational analysis revealed an autosomal dominant...

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Identifiers

PMID: 33541266
DOI: 10.1186/s12882-021-02254-9
PMCID: PMC7863463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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