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Transcriptome sequencing revealed the inhibitory mechanism of ketoconazole on clinical Microsporum canis

14 Dec 2020

Abstract excerpt

Background: Microsporum canis is a zoonotic disease that can cause dermatophytosis in animals and humans. Objectives: In clinical practice, ketoconazole (KTZ) and other imidazole drugs are commonly used to treat M. canis infection, but its molecular mechanism is not completely understood. The antifungal mechanism of KTZ needs to be studied in detail. Methods: In this study, one strain of fungi was isolated from a...

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PMID: 33522156
DOI: 10.4142/jvs.2021.22.e4

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