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Article

[Rare variants of HSPB1 are probably associated with amyotrophic lateral sclerosis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 30 Jan 2021

Chen Junyi, Liu Xiangyi, Xu Yingsheng, Fan Dongsheng

Abstract excerpt

OBJECTIVE: To explore the association between rare HSPB1 variants and amyotrophic lateral sclerosis (ALS). METHODS: We performed next-generation sequencing for 166 Chinese ALS patients to screen for possible pathogenic rare variants of HSPB1. The control individuals were obtained from 1000 Genome Project and an in-house whole-exome sequencing database. The Sequence Kernel Association Test (SKAT) and the...

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Identifiers

PMID: 33509756
DOI: 10.12122/j.issn.1673-4254.2021.01.10
PMCID: PMC7867492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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