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Urinary- and Plasma-Derived Exosomes Reveal a Distinct MicroRNA Signature Associated With Albuminuria in Hypertension

25 Jan 2021

Abstract excerpt

Urinary albumin excretion (UAE) is a marker of cardiovascular risk and renal damage in hypertension. MicroRNAs (miRNAs) packaged into exosomes function as paracrine effectors in cell communication and the kidney is not exempt. This study aimed to state an exosomal miRNA profile/signature associated to hypertension with increased UAE and the impact of profibrotic TGF-β1 (transforming growth factor β1) on exosomes...

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Extracellular vesicles in disease
MicroRNA in disease regulation
Pregnancy and preeclampsia studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33486986
DOI: 10.1161/hypertensionaha.120.16598

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