Article
In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes.
Journal of the American Society of Nephrology : JASN - 1 Mar 2021
Ravindran Aishwarya, Casal Moura Marta, Fervenza Fernando C, Nasr Samih H, Alexander Mariam P, Fidler Mary E, Herrera Hernandez Loren P, Zhang Pingchuan, Grande Joseph P, Cornell Lynn D, Gross Lou Ann, Negron Vivian, Jenson Grace E, Madden Benjamin J, Charlesworth M Cristine, Sethi Sanjeev
Abstract excerpt
BACKGROUND: In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens, biomarkers, or both. In this study, we validate the EXT1/EXT2 findings in a large cohort of membranous lupus nephritis. METHODS: We conducted a retrospective cohort study of patients with membranous lupus nephritis, and performed...
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