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Article

Genetic diseases of the Kennedy pathways for membrane synthesis.

The Journal of biological chemistry - 18 Dec 2020

Tavasoli Mahtab, Lahire Sarah, Reid Taryn, Brodovsky Maren, McMaster Christopher R

Abstract excerpt

The two branches of the Kennedy pathways (CDP-choline and CDP-ethanolamine) are the predominant pathways responsible for the synthesis of the most abundant phospholipids, phosphatidylcholine and phosphatidylethanolamine, respectively, in mammalian membranes. Recently, hereditary diseases associated with single gene mutations in the Kennedy pathways have been identified. Interestingly, genetic diseases within the...

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PMID: 33454021
DOI: 10.1074/jbc.REV120.013529
PMCID: PMC7762932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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