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Article

Use of hiPSC to explicate genomic predisposition to anthracycline-induced cardiotoxicity.

Pharmacogenomics - 1 Jan 2021

Magdy Tarek, Burridge Paul W

Abstract excerpt

The anticancer agents of the anthracycline family are commonly associated with the potential to cause severe toxicity to the heart. To solve the question of why particular a patient is predisposed to anthracycline-induced cardiotoxicity (AIC), researchers have conducted numerous pharmacogenomic studies and identified more than 60 loci associated with AIC. To date, none of these identified loci have been developed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33448871
DOI: 10.2217/pgs-2020-0104
PMCID: PMC7923254

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