Article
A functional polymorphism of inhibin alpha subunit at miR-181b-1-3p-binding site regulates proliferation and apoptosis of chicken ovarian granular cells.
Cell and tissue research - 1 May 2021
Cui Zhifu, Shen Xiaoxu, Zhang Xianxian, Li Fugui, Amevor Felix Kwame, Zhu Qing, Wang Yan, Li Diyan, Shu Gang, Tian Yaofu, Zhao Xiaoling
Abstract excerpt
INHA, the gene encoding the inhibin alpha subunit, was involved in folliculogenesis in mammals, but no study was reported for its working pathway in birds. Here we hypothesize that gene polymorphism in INHA 3'UTR might influence miRNAs binding efficiency and further affect the function of this gene. Thus, we investigated the association between the 3'UTR single-nucleotide polymorphisms (SNPs) in INHA and the...
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