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Generation of two induced pluripotent stem cell lines from a patient with recessive inherited retinal disease caused by compound heterozygous mutations in SNRNP200.

Stem cell research - 1 Mar 2021

Zhang Dan, McLenachan Samuel, Chen Shang-Chih, Zaw Khine, Alziyadat Yaqin, Zhang Xiao, Lamey Tina M, Thompson Jennifer A, McLaren Terri L, Mellough Carla, De Roach John N, Chen Fred K

Abstract excerpt

The human induced pluripotent stem cell (iPSC) lines LEIi015-A and LEIi015-B were derived from a patient with inherited retinal disease caused by compound heterozygous mutations in the SNRNP200 gene (c.[1792C>T];[3341T>C]). Dermal fibroblasts were transfected with episomal plasmids carrying transgenes encoding OCT4, SOX2, KLF4, L-MYC, LIN28, mir302/367 microRNA and shRNA for P53. The clonal iPSC lines LEIi015-A...

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PMID: 33429167
DOI: 10.1016/j.scr.2020.102154

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Generation of two induced pluripotent stem cell lines from a patient with recessive inherited retinal disease caused by compound heterozygous mutations in SNRNP200.PMID 33429167Read ↗

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