Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirus

30 Nov 2020

Abstract excerpt

Antiviral therapies targeting the pandemic coronavirus disease 2019 (COVID-19) are urgently required. We studied an already-approved botanical drug cepharanthine (CEP) in a cell culture model of GX_P2V, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related virus. RNA-sequencing results showed the virus perturbed the expression of multiple genes including those associated with cellular stress...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Peptides and Activities
Share to Berberine and alkaloids research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33423067
DOI: 10.1093/bib/bbaa387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome analysis of cepharanthine against a SARS-CoV-2-related coronavirusPMID 33423067Read ↗

Manipulation of the unfolded protein response: a pharmacological strategy against coronavirus infectionSemantic proximity Read ↗

Bulk and single-cell gene expression profiling of SARS-CoV-2 infected human cell lines identifies molecular targets for therapeutic interventionSemantic proximity Read ↗

In Search of Herbal Anti-SARS-Cov2 CompoundsSemantic proximity Read ↗

A mixture of essential oils from three Cretan Aromatic Plants inhibits SARS-CoV-2 proliferation: A Proof-of-Concept intervention study in ambulatory patientsSemantic proximity Read ↗

Repurposing Astragalus Polysaccharide PG2 for Inhibiting ACE2 and SARS-CoV-2 Spike Syncytial Formation and Anti-Inflammatory EffectsSemantic proximity Read ↗

SARS-CoV-2 fears green: the chlorophyll catabolite Pheophorbide a is a potent antiviralSemantic proximity Read ↗

The rocaglate CR-31-B (−) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivoSemantic proximity Read ↗

<i>In vitro</i> efficacy of Artemisinin-based treatments against SARS-CoV-2Semantic proximity Read ↗

In vitro efficacy of artemisinin-based treatments against SARS-CoV-2Semantic proximity Read ↗

Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 variants of concern by HMOX-1 upregulation in human cellsSemantic proximity Read ↗

A mixture of essential oils from three Cretan Aromatic Plants (thyme, Greek sage and Cretan dittany, CAPeo) inhibits SASR-CoV-2 proliferation:<i>in vitro</i>evidence and a Proof-of-Concept intervention study in mild ambulatory COVID-19-positive patientsSemantic proximity Read ↗

SARS‐CoV‐2 infection activates CREB/CBP in cellular cyclic AMP‐dependent pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.