Article
Mutation analysis of the spike protein in Italian feline infectious peritonitis virus and feline enteric coronavirus sequences.
Research in veterinary science - 1 Mar 2021
Decaro N, Mari V, Lanave G, Lorusso E, Lucente M S, Desario C, Colaianni M L, Elia G, Ferringo F, Alfano F, Buonavoglia C
Abstract excerpt
Feline coronavirus (FCoV) exists as two different genotypes, FCoV type I and II, each including two biotypes, feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV), the latter being a virulent variant originating from the former virus. Recently, two amino acid substitutions, M1058L and S1060A, within the spike protein have been associated to the FECV/FIPV virulence change. In this...
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