Article
POLG Mutations Are Probably Rare in the Han Chinese Population.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 31 Dec 2020
Yang Kun Fang, Meng Lin Yi, Zhang Yuan Feng, Yang Yong Chen, Cheng Hong Yi, Jiang Zhi Hu, Zhang Hong, Chen Yu Cai
Abstract excerpt
Objective Mutations in polymerase gamma gene (POLG) are believed to be an important cause of early and juvenile onset of non-syndromic intractable epilepsy. The aim of this study is to investigate the incidence/prevalence of POLG pathogenic variants in epilespy patients of Han population through sequencing it.Methods Han Chinese patients with seizures prior valproic acid (VPA) exposure at Shanghai Children's...
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