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Article

Association of rs12722 COL5A1 with pulmonary tuberculosis: a preliminary case-control study in a Kazakhstani population.

Molecular biology reports - 1 Jan 2021

Zhetkenev Sanzhar, Khassan Ayauly, Khamzina Armanay, Issanov Alpamys, Crape Byron, Akilzhanova Ainur, Yerezhepov Dauren, Kozhamkulov Ulan, Chan Chee Kai

Abstract excerpt

Lung cavitation is the classic hallmark of TB, which facilitates the disease development and transmission. It involves the degradation of lung parenchyma which is mainly made up of collagen fibers by metalloproteinases (MMPs) produced by activated monocyte-derived cells, neutrophils and stromal cells. The following population-based preliminary case-control study of adults with TB (50) and controls (112) without...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33409715
DOI: 10.1007/s11033-020-06121-y

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