Article
DNA methylation mutants in Physcomitrella patens elucidate individual roles of CG and non-CG methylation in genome regulation.
Proceedings of the National Academy of Sciences of the United States of America - 29 Dec 2020
Domb Katherine, Katz Aviva, Harris Keith D, Yaari Rafael, Kaisler Efrat, Nguyen Vu H, Hong Uyen V T, Griess Ofir, Heskiau Karina G, Ohad Nir, Zemach Assaf
Abstract excerpt
Cytosine (DNA) methylation in plants regulates the expression of genes and transposons. While methylation in plant genomes occurs at CG, CHG, and CHH sequence contexts, the comparative roles of the individual methylation contexts remain elusive. Here, we present Physcomitrella patens as the second plant system, besides Arabidopsis thaliana, with viable mutants with an essentially complete loss of methylation in...
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